| Disease Name | phenotype | Inheritance Mode | Chr Location | Mutation Type | Gene Name | mRNA Variant | Protein Variant | Effect | Reference |
| Obesity (LEP) | obese | Autosomal Recessive | 7q32.1 | Deletion | LEP | 1-44del42 | Frame shift mutation | 0/Saeed et al., 2015 | |
| Obesity (LEP) | obese | Autosomal Recessive | 7q32.1 | Missense | LEP | 350G>A | Cys117Tyr | Amino Acid Substitution | 0/Saeed et al., 2015 |
| Obesity (LEP) | obese | Autosomal Recessive | 7q32.1 | Missense | LEP | 313C>T | Arg105Trp | Amino Acid Substitution | 0/Saeed et al., 2015 |
| Obesity (LEP) | obese | Autosomal Recessive | 7q32.1 | Deletion | LEP | 398delG | Gly133Valfs*14 | Frame shift mutation & PTC | 0/Saeed et al., 2015 |
| Obesity (LEP) | obese | Autosomal Recessive | 7q32.1 | Deletion | LEP | 393delG | 147* | Frame shift mutation & PTC | 0/Montague et al., 1997 |
