| Disease Name | phenotype | Inheritance Mode | Chr Location | Mutation Type | Gene Name | mRNA Variant | Protein Variant | Effect | Reference |
| Hearing Impairment 28 (DFNB28, TRIOBP) | Profound prelingual hearing impairment | Autosomal Recessive | 22q13 | Nonsense | TRIOBP | 2362C>T | Arg788* | Premature Termination | 0/Riazuddin et al., 2006 |
| Hearing Impairment 28 (DFNB28, TRIOBP) | Profound prelingual hearing impairment | Autosomal Recessive | 22q13 | Nonsense | TRIOBP | 3202C>T | Arg1068* | Premature Termination | 0/Riazuddin et al., 2006 |
| Hearing Impaiment (TRIOBP) | Hearing loss | Autosomal Recessive | 22q13.1 | Delation | TRIOBP | c.3460_3461delCT | p.(Leu1154Alafs*29) | Frameshift | Richard et al., 2019/2019 |
| Hearing Impaiment (TRIOBP) | Hearing loss | Autosomal Recessive | 22q13.1 | Delation | TRIOBP | c.3634_3646delCTGATCCCCCAAG | p.(Leu1212Cysfs*22) | Frameshift | Richard et al., 2019/2019 |
| Hearing Impaiment (TRIOBP) | Hearing loss/Deafness 28 | Autosomal Recessive | 22q13.1 | Substitution | TRIOBP | c.1952C>T | p.Ser651Phe | Missense | Zhou et al., 2020/2020 |
