| Disease Name | phenotype | Inheritance Mode | Chr Location | Mutation Type | Gene Name | mRNA Variant | Protein Variant | Effect | Reference |
| Hearing Impairment 8/10 (DFNB8/10, TMPRSS3) | Prelingual hearing impairment | Autosomal Recessive | 21q22.3 | Missense | TMPRSS3 | 1219T>C | Cys407Arg | Amino Acid Substitution | 0/Ben-Yosef et al., 2001 |
| Hearing Impairment 8/10 (DFNB8/10, TMPRSS3) | Prelingual hearing impairment | Autosomal Recessive | 21q22.3 | Missense | TMPRSS3 | 325C>T | Arg109Trp | Amino Acid Substitution | 0/Ben-Yosef et al., 2001 |
| Hearing Impairment 8/10 (DFNB8/10, TMPRSS3) | Prelingual hearing impairment | Autosomal Recessive | 21q22.3 | Missense | TMPRSS3 | 581G>T | Cys194Phe | Amino Acid Substitution | 0/Ben-Yosef et al., 2001 |
| Hearing Impairment 8/10 (DFNB8/10, TMPRSS3) | Prelingual hearing impairment | Autosomal Recessive | 21q22.3 | Deletion | TMPRSS3 | 207delC | Frame shift mutation | 0/Ahmed et al., 2004 | |
| Hearing Impaiment (TMPRSS3) | Hearing loss | Autosomal Recessive | 21q22.3 | Substitution | TMPRSS3 | c.783–1G>T | Splice error | Splice error | Richard et al., 2019/2019 |
| Hearing Impaiment (TMPRSS3) | Hearing loss/Deafness 8/10 | Autosomal Recessive | 21q22.3 | Substitution | TMPRSS3 | c.941?T>C | p.Leu314Pro | Missense | Zhou et al., 2020/2020 |
| Hearing Impairment 8/10 (DFNB8/10, TMPRSS3) | Prelingual hearing impairment, Deafness 8/10 | Autosomal Recessive | 21q22.3 | Substitution | TMPRSS3 | 726C>G | Cys242Trp | Missense | Shafique et al., 2014/2014 |
